Researchers discover 'Humpty-Dumpty' water-based mechanism of human sex reversal at edge of developmental ambiguity

Researchers discover ‘Humpty-Dumpty’ water-based mechanism of human sex reversal at edge of developmental ambiguity

Structural models of wild-type and mutant side chains. (A) L-shaped SRY HMG box (α-helices labeled α1-3) bound to a DNA target site (light green spheres; PDB entry 1J46) (7). Shown at right is an expanded view of boxed region depicting minor-wing mini-core (full-length numbering scheme). (B) Rigid-body substitution of mutant side chains at box position…

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Italy business and consumer morale rises in December, but manufacturers more downbeat

Italy business and consumer morale rises in December, but manufacturers more downbeat

ROME, Dec 23 (Reuters) – Morale amongst Italian businesses and consumers rose in December, data showed on Friday, although the manufacturing sector was more downbeat. National statistics institute ISTAT’s composite business morale index, combining surveys of the manufacturing, retail, construction and services sectors, climbed to 107.8 in December, compared with November’s reading of 106.5. The…

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